Why tires wear unevenly in the first place
Each position on a vehicle asks something different of its tire. On a front-wheel-drive car, the front tires steer, carry the engine weight, and put down the power, so they wear faster. On a rear-wheel-drive pickup, the rear tires drive, while the fronts take the steering scrub. Left and right differ too, because roads are crowned and turns are not evenly split.
Left alone, a set of four ends up with two worn tires and two with tread to spare. Rotation evens that out, so the set wears together and can be replaced together.

